Autoimmune Thyroid Disease

An Unfortunate and Lengthy Adventure in Misdiagnosis

Propionates, methyl stealers, and multiple sclerosis

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I was interested to note that vitamin C eases reactions to propionates, those nasty bread additives.

Propionic acid is produced biologically from the metabolic breakdown of fatty acids containing odd numbers of carbon atoms, and also the breakdown of some amino acids. Bacteria of the genus Propionibacterium produce propionic acid as the end product of their anaerobic metabolism. These bacteria are commonly found in the stomachs of ruminants, and their activity is partially responsible for the odor of both Swiss cheese and sweat. Propionic acid

Odd chain fatty acids have also been associated with multiple sclerosis. Odd chain fatty acids are unusual in nature, but are present in larger than average amounts in the bodies of MS sufferers. They attack the myelin sheath that protects nerves and neurotransmitters from damage.

I wonder if propionibacteria can live in the human intestines? They can and do live on the skin: propionibacteria are the cause of acne.

There are multiple sclerosis failsafers who appear to be doing well.

Multiple sclerosis has also been associated with deficiencies in folic acid, B12, and B6. This is usually regarded as being because of their importance in the formation of myelin. They are also important to the methylation cycle.

Groves noted some time ago that MS might have a bread connection, but blamed it on the bread not being fermented. He’s not the first to make these connections with bread.

While propionic acid, interestingly, contains a methyl group, propionate doesn’t.

Propionic acid: CH3CH2COOH

Propionate: C2H5COO−

A CH3 group is a methyl group.

Propionate is obviously affecting the methylation cycle, but in this case in a negative way. Is there such thing as a methyl-stealer?

What does propionate do when it meets a methyl donor?

Methyl propionate: CH3(C2H5COO)

Is it stealing methyl groups?

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Written by alienrobotgirl

10 April, 2006 at 6:28 pm

Posted in Methyl Donors

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